cdna library Archives - Gen9 Genetics

In higher eukaryotes, many genes are transcribed into mRNA only in specialized cell types. For example, mRNAs that encode globin proteins are found only in erythrocyte precursor cells, called reticulocytes. Also, the mRNA encoding albumin, the main protein in serum, is produced only in liver cells where albumin is synthesized. Specific DNA sequences expressed as mRNA in a particular cell type can be cloned by synthesizing DNA copies of the mRNAs isolated from that cell type and then cloning the DNA copies into plasmid vectors.